As the 2025 NFL season kicks off, fantasy football enthusiasts are eager to identify players who could make a significant impact in Week 1. Several athletes stand out as potential game-changers, each bringing unique strengths and circumstances that could influence their performance.
Baker Mayfield’s Strong Start
Baker Mayfield, quarterback for the Tampa Bay Buccaneers, enters the season after a stellar performance in 2024, where he threw for 4,500 yards and 41 touchdowns. This week, he faces off against the Atlanta Falcons, in a matchup projected to be high-scoring with a total of 47.5 points according to ESPN BET. Despite injuries to key receivers Chris Godwin and Cade Otton, Mayfield has demonstrated his ability to succeed with backup players, making him a strong candidate to deliver top-tier fantasy points.
Running Backs to Consider
Another player to watch is James Conner of the Arizona Cardinals. Known for his durability, Conner has played at least 13 games in each of the last five seasons and has consistently surpassed 1,000 scrimmage yards. In Week 1, he is expected to handle the ball 16-18 times, which positions him as a top-15 running back against the New Orleans Saints, who allowed the seventh-most fantasy points to running backs last season.
On the other hand, D’Andre Swift of the Chicago Bears may face challenges in his first game. Under the new offense led by Ben Johnson, Swift’s role remains uncertain, especially with competition from Roschon Johnson and potentially Jamaal Williams. The matchup against the Minnesota Vikings, who allowed the second-fewest rushing yards in 2024, further complicates expectations. Swift’s low average of 3.8 yards per carry last year suggests that fantasy managers should prepare for modest returns.
Wide Receivers to Watch
Wide receiver Jerry Jeudy of the Cleveland Browns could thrive this week, especially with Joe Flacco starting as quarterback. Flacco’s history shows that his top receivers average 21.1 fantasy points per game, making Jeudy a solid WR2 option. With a projected volume of 8-10 targets, he is well-positioned to capitalize against the Cincinnati Bengals.
Conversely, Courtland Sutton from the Denver Broncos might face a tougher road ahead. Coming off a productive season with 81 catches and 1,081 yards, Sutton now must contend with a run-heavy strategy under coach Sean Payton. Facing the Tennessee Titans, who allowed the fewest receiving yards last season, Sutton’s potential may be capped, suggesting he could deliver only high-end flex numbers in this matchup.
Breakout Candidates and Tight End Prospects
Ricky Pearsall, the leading wide receiver for the San Francisco 49ers, is another player to keep an eye on. As injuries and suspensions have left the 49ers’ receiving corps thin, Pearsall is poised for a breakout against the Seattle Seahawks. With a favorable matchup and the team’s reliance on high-yards-after-catch (YAC) plays, Pearsall could significantly contribute to the 49ers’ offense.
Lastly, Sam LaPorta, tight end for the Detroit Lions, faces challenges following the departure of former offensive coordinator Ben Johnson. Despite potential dips in production, LaPorta’s matchup against the Green Bay Packers, who allowed the sixth-highest catch rate to tight ends last year, provides a glimmer of hope. This game is also projected for a total of 47.5 points, suggesting ample opportunities for LaPorta to shine.
As the season begins, fantasy football managers must navigate these intriguing matchups and individual performances. Each player’s potential highlights the unpredictability and excitement that makes fantasy sports so engaging.
