5 September, 2025
study-links-artificial-sweeteners-to-accelerated-brain-aging

A recent study conducted in Brazil has raised concerns about the impact of artificial sweeteners on cognitive health. Researchers tracked over 12,000 adults for a period of eight years and found that the consumption of six common sweeteners was associated with accelerated brain aging. The substances investigated include aspartame, saccharin, acesulfame potassium, erythritol, xylitol, and sorbitol.

The findings revealed that individuals consuming the highest amounts of these sweeteners experienced an increase in brain aging equivalent to approximately 1.6 years compared to those who consumed the least. The high-consumption group averaged around 190 to 200 mg per day, roughly the amount found in a single can of Diet Coke.

Health Implications of Artificial Sweeteners

Researchers suspect that the negative effects of these sweeteners may stem from their potential to break down into toxic compounds that can damage brain cells or contribute to increased inflammation in the brain. The study highlighted that erythritol, in particular, has been linked to reduced blood flow and an elevated risk of stroke.

The impact of these sweeteners was most pronounced among middle-aged adults, especially those with diabetes. Interestingly, older adults over the age of 60 did not exhibit the same cognitive decline associated with sweetener consumption. This suggests that age and underlying health conditions may play a significant role in how artificial sweeteners affect cognitive function.

Dr. Thomas Monroe Holland, a researcher at Rush University in Chicago, emphasized the importance of dietary choices in midlife. He stated, “What we eat in midlife could affect your brain health for years to come.” This underscores the potential long-term implications of consuming artificial sweeteners, particularly for individuals in their middle years.

In contrast, the study found that tagatose, a natural sweetener found in fruit and dairy products, did not show any association with cognitive decline. This raises questions about the safety and health implications of different types of sweeteners and their effects on brain health.

As public awareness grows regarding the health impacts of diet, these findings may prompt individuals to reconsider their consumption of artificial sweeteners. The research serves as a reminder that choices made today can have lasting effects on health and well-being in the future.